Protein tyrosine Phosphatase, Receptor Type, N Polypeptide 2 (PTPRN2) Antikörper

Details zu Produkt Nr. ABIN6568471
Target
Reaktivität
Human, Maus, Ratte
50
15
6
Wirt
Kaninchen
43
7
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
3
3
3
3
3
1
1
1
1
1
1
Applikation
Western Blotting (WB)
46
33
3
3
1
1
1
1
Optionen
Immunogen Recombinant protein of human PTPRN2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung PTPRN2 (PTPRN2 Antibody Abstract)
Hintergrund

Synonyms: IA 2beta ,IA2beta ,IAR,IAR/receptor like protein tyrosine phosphatase,ICAAR,Islet cell autoantigen related protein,Islet cell autoantigen-related protein,Phogrin,Protein tyrosine phosphatase receptor pi ,Protein tyrosine phosphatase, receptor type, N polypeptide 2,PTPR2,Ptprn2,PTPRP ,R PTP N2,R-PTP-N2,Receptor-type tyrosine-protein phosphatase N2,Tyrosine phosphatase IA 2 beta

Background: This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 111kDa

Calculated_MW: 108kDa/109kDa/111kDa/114kDa

Gen-ID 5799
UniProt Q92932
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Protein tyrosine Phosphatase, Receptor Type, N Polypeptide 2 (PTPRN2) antibody (ABIN6568471) Western blot analysis of extracts of various cell lines, using PTPRN2 antibody.