PTPRN2 Antikörper

Produktnummer ABIN6568471

Produktdetails anti-PTPRN2 Antikörper

Target: PTPRN2 (Protein tyrosine Phosphatase, Receptor Type, N Polypeptide 2 (PTPRN2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRN2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PTPRN2 (NP_570858.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PTPRN2

Target: PTPRN2 (Protein tyrosine Phosphatase, Receptor Type, N Polypeptide 2 (PTPRN2))

Andere Bezeichnung: PTPRN2 (PTPRN2 Produkte)

Synonyme: IA-2beta antikoerper, IAR antikoerper, ICAAR antikoerper, PTPRP antikoerper, R-PTP-N2 antikoerper, 4930425H11Rik antikoerper, IA2beta antikoerper, PTP-NP antikoerper, Phol antikoerper, mKIAA0387 antikoerper, phogrin antikoerper, protein tyrosine phosphatase, receptor type N2 antikoerper, protein tyrosine phosphatase, receptor type, N polypeptide 2 antikoerper, PTPRN2 antikoerper, Ptprn2 antikoerper

Hintergrund: This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 111kDa

Calculated_MW: 108kDa/109kDa/111kDa/114kDa

Gen-ID: 5799

UniProt: Q92932