DAD1 Antikörper

Produktnummer ABIN6568449

Der Kaninchen Polyklonal anti-DAD1 Antikörper (ABIN6568449) detektiert spezifisch DAD1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für DAD1 Antikörper (ABIN6568449)

Target: DAD1 (Defender Against Cell Death 1 (DAD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DAD1 Antikörper

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human DAD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DAD1

Target: DAD1 (Defender Against Cell Death 1 (DAD1))

Andere Bezeichnung: DAD1

Hintergrund:

Synonyms: DAD 1,DAD-1,dad1,DAD1,Defender against cell death 1,Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1,Oligosaccharyl transferase subunit DAD1,OST 2,OST2

Background: DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.

Molekulargewicht:

Observed_MW: 22kDa

Calculated_MW: 12kDa

Gen-ID: 1603

UniProt: P61803