Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4) Antikörper

Details zu Produkt Nr. ABIN6568294
Target
Reaktivität
Human, Maus
52
42
39
1
1
Wirt
Kaninchen
46
14
11
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
Western Blotting (WB)
45
30
13
11
9
6
5
2
2
Optionen
Immunogen A synthetic peptide of human SLC6A4
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung SLC6A4 (SLC6A4 Antibody Abstract)
Hintergrund

Synonyms: 5 HTT,5 HTTLPR,5 hydroxytryptamine (serotonin) transporter,5 hydroxytryptamine transporter,5HT transporter,5HTT,hSERT,HTT,Na+/Cl- dependent serotonin transporter,OCD1,SC6A4,Serotonin transporter 1,SERT,SERT1,Slc6a4,Sodium dependent serotonin transporter,Sodium-dependent serotonin transporter,Solute carrier family 6 (neurotransmitter transporter) member 4,solute carrier family 6 (neurotransmitter transporter,serotonin),member 4,Solute carrier family 6 member 4

Background: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Molekulargewicht

Observed_MW: 69kDa

Calculated_MW: 70kDa/74kDa

Gen-ID 6532
UniProt P31645
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4) antibody (ABIN6568294) Western blot analysis of extracts of various cell lines, using SLC6A4 antibody.