NUDT15 Antikörper

Produktnummer ABIN6568286

Produktdetails anti-NUDT15 Antikörper

Target: NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUDT15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human NUDT15 (NP_060753.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NUDT15

Target: NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))

Andere Bezeichnung: NUDT15 (NUDT15 Produkte)

Synonyme: MTH2 antikoerper, RP11-90M2.1 antikoerper, 6530403O17 antikoerper, A730068G11Rik antikoerper, nudix hydrolase 15 antikoerper, nudix (nucleoside diphosphate linked moiety X)-type motif 15 antikoerper, NUDT15 antikoerper, Nudt15 antikoerper

Hintergrund: This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.

Molekulargewicht:

Observed_MW: 19kDa

Calculated_MW: 18kDa

Gen-ID: 55270

UniProt: Q9NV35