NUDT15 Antikörper (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15)

Details for Product anti-NUDT15 Antibody No. ABIN6568286
Target
Reaktivität
Maus, Ratte
26
10
2
2
2
2
2
2
1
1
1
Wirt
Kaninchen
26
Klonalität
Polyklonal
Konjugat
Dieser NUDT15 Antikörper ist unkonjugiert
3
3
3
2
2
2
Applikation
Western Blotting (WB)
22
18
18
15
2
1
1
Optionen
Immunogen Recombinant protein of human NUDT15
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung NUDT15 (NUDT15 Antibody Abstract)
Hintergrund

Synonyms: 8-dihydro-8-oxoguanine triphosphatase NUDT15,8-oxo-dGTPase NUDT15,A730068G11Rik,EC 3.1.6.-,FLJ10956,MGC104352,MTH2,MutT homolog 2,Nucleoside diphosphate-linked moiety X motif 15,NUD15,Nudix (nucleoside diphosphate linked moiety X)-type motif ,Nudix motif 15,NUDT15,OTTHUMP00000018389,Probable 7,Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15,RP11-90M2.1

Background: This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified.

Molekulargewicht

Observed_MW: 19kDa

Calculated_MW: 18kDa

Gen-ID 55270
UniProt Q9NV35
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15) antibody (ABIN6568286) Western blot analysis of extracts of mouse spleen, using NUDT15 antibody.