NUDT15 Antikörper (C-Term)

Produktnummer ABIN654983

Produktdetails anti-NUDT15 Antikörper

Target: NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))

Bindungsspezifität: AA 89-118, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUDT15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NUDT15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the C-terminal region of human NUDT15.

Klon: RB28179

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. WB: 1:500. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu NUDT15

Target: NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))

Andere Bezeichnung: NUDT15 (NUDT15 Produkte)

Synonyme: MTH2 antikoerper, RP11-90M2.1 antikoerper, 6530403O17 antikoerper, A730068G11Rik antikoerper, nudix hydrolase 15 antikoerper, nudix (nucleoside diphosphate linked moiety X)-type motif 15 antikoerper, NUDT15 antikoerper, Nudt15 antikoerper

Hintergrund: Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.

Molekulargewicht: 18609

Gen-ID: 55270

NCBI Accession: NP_060753

UniProt: Q9NV35