Cathepsin K Antikörper (AA 97-126)

Produktnummer ABIN656812

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cathepsin K in WB, IHC (p) und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Cathepsin K Antikörper (AA 97-126) (ABIN656812)

Target: Cathepsin K (CTSK)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin K Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: RB19253

Produktdetails anti-Cathepsin K Antikörper

Bindungsspezifität: AA 97-126

Homologie: B, Pr

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CTSK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human CTSK.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: CTSK Antibody (Center E112) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu Cathepsin K

Target: Cathepsin K (CTSK)

Andere Bezeichnung: CTSK

Hintergrund: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq].

Molekulargewicht: 36966

Gen-ID: 1513

NCBI Accession: NP_000387

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades