COL1A1 Antikörper (Collagen, Type I, alpha 1)

Details for Product anti-COL1A1 Antibody No. ABIN6568019
Target
Reaktivität
Human, Maus
62
32
30
12
5
4
4
3
2
2
1
1
1
Wirt
Kaninchen
79
10
Klonalität
Polyklonal
Konjugat
Dieser COL1A1 Antikörper ist unkonjugiert
10
6
5
2
2
2
2
2
2
2
2
2
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
66
41
39
17
10
7
4
3
2
1
1
1
Optionen
Immunogen A synthetic peptide of human COL1A1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung COL1A1 (COL1A1 Antibody Abstract)
Hintergrund

Synonyms: COL1A1,Alpha 1 type I collagen,Alpha-1 type I collagen,CO1A1,COL1A1,Collagen alpha-1(I) chain,Collagen type I alpha 1,Procollagen type I C terminal propeptide

Background: This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Molekulargewicht

Observed_MW: 95kDa, 110kDa

Calculated_MW: 138kDa

Gen-ID 1277
UniProt P02452
Pathways Sensory Perception of Sound, Autophagie, Growth Factor Binding
Applikations-hinweise WB 1:500 - 1:1000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Collagen, Type I, alpha 1 (COL1A1) antibody (ABIN6568019) Western blot analysis of extracts of mouse heart, using COL1A1 antibody.
Image no. 2 for anti-Collagen, Type I, alpha 1 (COL1A1) antibody (ABIN6568019) Immunohistochemistry of paraffin-embedded human prostate cancer using COL1A1 antibody.
Image no. 3 for anti-Collagen, Type I, alpha 1 (COL1A1) antibody (ABIN6568019) Immunohistochemistry of paraffin-embedded human esophagus using COL1A1 antibody.