Glutathione S-Transferase mu 2 (Muscle) (GSTM2) Antikörper

Details zu Produkt Nr. ABIN6568004
Target
Reaktivität
Human, Maus
34
18
10
1
Wirt
Kaninchen
31
10
Klonalität
Polyklonal
Konjugat
Unkonjugiert
4
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
32
17
16
11
6
6
2
2
1
1
1
1
Optionen
Immunogen Recombinant protein of human GSTM2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung GSTM2 (GSTM2 Antibody Abstract)
Hintergrund

Synonyms: Glutathione S alkyltransferase M2,Glutathione S aralkyltransferase M2,Glutathione S aryltransferase M2,Glutathione S transferase 4,Glutathione S transferase M1,Glutathione S transferase M2 (muscle),Glutathione S transferase Mu 2 (muscle),Glutathione S transferase Mu 2,Glutathione S-transferase Mu 2,GST class mu 2,GST class-mu 2,GST muscle,GST4,GSTM,GSTM2,GSTM2-2,GSTM2,GTHMUS,MGC117303,S (hydroxyalkyl)glutathione lyase M2

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.

Molekulargewicht

Observed_MW: 27kDa

Calculated_MW: 22kDa/25kDa

Gen-ID 2946
UniProt P28161
Pathways Negative Regulation of Transporter Activity
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Glutathione S-Transferase mu 2 (Muscle) (GSTM2) antibody (ABIN6568004) Western blot analysis of extracts of mouse testis, using GSTM2 antibody.
Image no. 2 for anti-Glutathione S-Transferase mu 2 (Muscle) (GSTM2) antibody (ABIN6568004) Immunohistochemistry of paraffin-embedded human colon using GSTM2 Antibody.
Image no. 3 for anti-Glutathione S-Transferase mu 2 (Muscle) (GSTM2) antibody (ABIN6568004) Immunofluorescence analysis of A549 cells using GSTM2 antibody.