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APEH Antikörper

Dieses Anti-APEH-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von APEH in IF. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN6567985

Kurzübersicht für APEH Antikörper (ABIN6567985)

Target

Alle APEH Antikörper anzeigen
APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

Reaktivität

  • 51
  • 17
  • 15
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 51
Kaninchen

Klonalität

  • 51
Polyklonal

Konjugat

  • 20
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser APEH Antikörper ist unkonjugiert

Applikation

  • 33
  • 13
  • 13
  • 12
  • 7
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
Immunofluorescence (IF)
  • Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein of human APEH (NP_001631.3).

    Isotyp

    IgG
  • Applikationshinweise

    IF 1:50-1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Konservierungsmittel

    Sodium azide

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    APEH (N-Acylaminoacyl-Peptide Hydrolase (APEH))

    Andere Bezeichnung

    APEH

    Hintergrund

    This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.

    Molekulargewicht

    Observed_MW: 80-108kDa

    Calculated_MW: 81kDa

    Gen-ID

    327

    UniProt

    P13798
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