TNFRSF11A Antikörper (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator)

Details for Product anti-TNFRSF11A Antibody No. ABIN6567926
Target
Reaktivität
Human, Maus, Ratte
63
33
27
Wirt
Kaninchen
54
19
4
Klonalität
Polyklonal
Konjugat
Dieser TNFRSF11A Antikörper ist unkonjugiert
5
5
3
2
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
38
27
15
13
10
9
5
5
3
2
1
1
1
Optionen
Immunogen Recombinant protein of human TNFRSF11A
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung TNFRSF11A (TNFRSF11A Antibody Abstract)
Hintergrund

Synonyms: CD 265,CD265,FEO,LOH18CR1,Loss of heterozygosity 18 chromosomal region 1,mRANK,ODFR,OFE,OPTB7,Osteoclast differentiation factor receptor,OSTS,Paget disease of bone 2,PDB 2,PDB2,RANK,Receptor activator of NF KB,Receptor activator of NF-KB,receptor activator of nuclear factor kappa B,TNF receptor superfamily member 11a,TNFRSF11A,TNR11,TRANCER,Tumor necrosis factor receptor superfamily member 11a NFKB activator,Tumor necrosis factor receptor superfamily member 11a activator of NFKB,Tumor necrosis factor receptor superfamily member 11A

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Molekulargewicht

Observed_MW: 90kDa

Calculated_MW: 28kDa/32kDa/36kDa/56kDa/64kDa/66kDa

Gen-ID 8792
UniProt Q9Y6Q6
Pathways NF-kappaB Signalweg
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) antibody (ABIN6567926) Western blot analysis of extracts of various cell lines, using TNFRSF11A antibody.
Image no. 2 for anti-Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A) antibody (ABIN6567926) Immunohistochemistry of paraffin-embedded mouse brain using TNFRSF11A antibody.