TAPBP Antikörper

Produktnummer ABIN6567907

Der Kaninchen Polyklonal Anti-TAPBP-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, TAPBP in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für TAPBP Antikörper (ABIN6567907)

Target: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAPBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TAPBP Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human TAPBP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TAPBP

Target: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Andere Bezeichnung: TAPBP

Hintergrund:

Synonyms: NGS 17,NGS-17,NGS17,TAP associated protein ,TAP binding protein ,TAP binding protein (tapasin),TAP BP,TAP-associated protein,TAP-binding protein,TAPA,Tapasin,TAPBP,TPN,TPSN,TPSN

Background: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Molekulargewicht:

Observed_MW: 50kDa

Calculated_MW: 38kDa/43kDa/47kDa/53kDa

Gen-ID: 6892

UniProt: O15533