Diazepam Binding Inhibitor Antikörper (DBI)

Details for Product anti-DBI Antibody No. ABIN6567860
Target
Reaktivität
Human, Maus
54
14
7
2
1
1
1
1
1
Wirt
Kaninchen
49
11
Klonalität
Polyklonal
Konjugat
Dieser Diazepam Binding Inhibitor Antikörper ist unkonjugiert
9
5
2
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
45
33
24
12
11
5
3
3
2
2
2
Optionen
Immunogen Recombinant protein of human DBI
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung DBI (DBI Antibody Abstract)
Hintergrund

Synonyms: ACBD 1,ACBD1,ACBP,ACBP,Acyl CoA binding domain containing 1,Acyl CoA binding protein,Acyl Coenzyme A binding domain containing 1,Acyl coenzyme A binding protein,Acyl-CoA-binding protein,CCK RP,CCKRP,Cholecystokinin releasing peptide trypsin sensitive,DBI,Diazepam-binding inhibitor,Endozepine,EP,GABA receptor modulator,MGC70414

Background: This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht

Observed_MW: 11kDa

Calculated_MW: 10kDa/11kDa/13kDa/14kDa/16kDa

Gen-ID 1622
UniProt P07108
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Diazepam Binding Inhibitor (DBI) antibody (ABIN6567860) Immunohistochemistry of paraffin-embedded mouse brain using DBI Antibody.
Image no. 2 for anti-Diazepam Binding Inhibitor (DBI) antibody (ABIN6567860) Western blot analysis of extracts of various cell lines, using DBI antibody.
Image no. 3 for anti-Diazepam Binding Inhibitor (DBI) antibody (ABIN6567860) Immunohistochemistry of paraffin-embedded human prostate using DBI Antibody.
Image no. 4 for anti-Diazepam Binding Inhibitor (DBI) antibody (ABIN6567860) Immunofluorescence analysis of MCF-7 cells using DBI antibody.