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ELANE Antikörper

ELANE Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6567736
  • Target Alle ELANE Antikörper anzeigen
    ELANE (Elastase, Neutrophil Expressed (ELANE))
    Reaktivität
    • 87
    • 25
    • 24
    • 4
    • 1
    Human, Maus
    Wirt
    • 67
    • 19
    • 4
    • 1
    Kaninchen
    Klonalität
    • 62
    • 29
    Polyklonal
    Konjugat
    • 47
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ELANE Antikörper ist unkonjugiert
    Applikation
    • 54
    • 38
    • 28
    • 17
    • 13
    • 10
    • 9
    • 9
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human ELANE (NP_001963.1).
    Isotyp
    IgG
    Top Product
    Discover our top product ELANE Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ELANE (Elastase, Neutrophil Expressed (ELANE))
    Andere Bezeichnung
    ELANE (ELANE Produkte)
    Synonyme
    ELA2 antikoerper, GE antikoerper, HLE antikoerper, HNE antikoerper, NE antikoerper, PMN-E antikoerper, SCN1 antikoerper, Ela2 antikoerper, F430011M15Rik antikoerper, ela2 antikoerper, ELANE antikoerper, elastase, neutrophil expressed antikoerper, proteinase 3 antikoerper, ELANE antikoerper, Elane antikoerper, prtn3 antikoerper
    Hintergrund
    Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19.
    Molekulargewicht

    Observed_MW: 29kDa

    Calculated_MW: 28kDa

    Gen-ID
    1991
    UniProt
    P08246
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