Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) Antikörper

Details zu Produkt Nr. ABIN6567646
Target
Reaktivität
Human
36
24
24
3
1
Wirt
Kaninchen
28
7
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
13
12
9
7
5
1
1
Optionen
Immunogen Recombinant Protein of human ITPR3
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung ITPR3 (ITPR3 Antibody Abstract)
Hintergrund

Synonyms: 4,5-trisphosphate receptor,5-trisphosphate receptor type 3,FLJ36205,Inositol 1,Inositol 1,4,5 trisphosphate receptor type 3,InsP3R3,IP3 receptor,IP3 receptor isoform 3,IP3R 3,IP3R,IP3R3,ITPR 3,ITPR3,ITPR3,Type 3 inositol 1,Type 3 inositol 1,4,5 trisphosphate receptor,Type 3 InsP3 receptor

Background: This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.

Molekulargewicht

Observed_MW: 300kDa

Calculated_MW: 304kDa

Gen-ID 3710
UniProt Q14573
Pathways Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3) antibody (ABIN6567646) Western blot analysis of extracts of various cell lines, using ITPR3 antibody.