SCARB2 Antikörper (Scavenger Receptor Class B, Member 2)

Details for Product anti-SCARB2 Antibody No. ABIN6567626
Target
Reaktivität
Human, Maus, Ratte
60
45
33
5
4
3
2
1
1
Wirt
Kaninchen
57
7
5
1
Klonalität
Polyklonal
Konjugat
Dieser SCARB2 Antikörper ist unkonjugiert
4
4
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Western Blotting (WB)
42
26
18
13
12
7
5
3
3
2
2
1
1
Optionen
Immunogen Recombinant protein of human SCARB2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung SCARB2 (SCARB2 Antibody Abstract)
Hintergrund

Synonyms: 85 kDa lysosomal membrane sialoglycoprotein,85 kDa lysosomal sialoglycoprotein scavenger receptor class B member 2,AMRF,CD36,CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II),CD36 antigen,CD36 antigen-like 2,CD36L2,EPM4,HLGP85,LGP85,LIMP 2,LIMP II,LIMP2,LIMPII,Lysosomal integral membrane protein II,Lysosome membrane protein 2,Lysosome membrane protein II,OTTHUMP00000160590,OTTHUMP00000219176,Scarb2,Scavenger receptor class B member 2,Scavenger receptor class B, member 2,SCRB2,SR BII,SRBII

Background: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht

Observed_MW: 80kDa

Calculated_MW: 37kDa/54kDa

Gen-ID 950
UniProt Q14108
Applikations-hinweise WB 1:1000 - 1:3000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Scavenger Receptor Class B, Member 2 (SCARB2) antibody (ABIN6567626) Western blot analysis of extracts of various cell lines, using SCARB2 antibody.