SCARB2 Antikörper

Produktnummer ABIN6567626

Produktdetails anti-SCARB2 Antikörper

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCARB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human SCARB2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000 - 1:3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SCARB2

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Andere Bezeichnung: SCARB2 (SCARB2 Produkte)

Hintergrund:

Synonyms: 85 kDa lysosomal membrane sialoglycoprotein,85 kDa lysosomal sialoglycoprotein scavenger receptor class B member 2,AMRF,CD36,CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II),CD36 antigen,CD36 antigen-like 2,CD36L2,EPM4,HLGP85,LGP85,LIMP 2,LIMP II,LIMP2,LIMPII,Lysosomal integral membrane protein II,Lysosome membrane protein 2,Lysosome membrane protein II,OTTHUMP00000160590,OTTHUMP00000219176,Scarb2,Scavenger receptor class B member 2,Scavenger receptor class B, member 2,SCRB2,SR BII,SRBII

Background: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 80kDa

Calculated_MW: 37kDa/54kDa

Gen-ID: 950

UniProt: Q14108