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MCM7 Antikörper

MCM7 Reaktivität: Human, Maus IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6567128
  • Target Alle MCM7 Antikörper anzeigen
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    Reaktivität
    • 118
    • 31
    • 25
    • 11
    • 10
    • 10
    • 9
    • 9
    • 4
    • 2
    • 1
    Human, Maus
    Wirt
    • 79
    • 37
    • 2
    Kaninchen
    Klonalität
    • 74
    • 44
    Polyklonal
    Konjugat
    • 76
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MCM7 Antikörper ist unkonjugiert
    Applikation
    • 79
    • 33
    • 32
    • 22
    • 21
    • 20
    • 13
    • 13
    • 13
    • 12
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MCM7 (NP_005907.3).
    Isotyp
    IgG
    Top Product
    Discover our top product MCM7 Primärantikörper
  • Applikationshinweise
    IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    Andere Bezeichnung
    MCM7 (MCM7 Produkte)
    Hintergrund
    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Molekulargewicht

    Observed_MW: 81kDa

    Calculated_MW: 44kDa/60kDa/81kDa

    Gen-ID
    4176
    UniProt
    P33993
    Pathways
    DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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