RHOC Antikörper (Ras Homolog Gene Family, Member C)

Details for Product anti-RHOC Antibody No. ABIN6567006
Target
Reaktivität
Human, Maus, Ratte
52
19
10
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Wirt
Kaninchen
41
12
Klonalität
Polyklonal
Konjugat
Dieser RHOC Antikörper ist unkonjugiert
4
3
3
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
44
31
20
4
3
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human RHOC
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung RHOC (RHOC Antibody Abstract)
Hintergrund

Synonyms: Aplysia RAS-related homolog 9,ARH 9,ARH9,ARHC,H9,MGC1448,MGC61427,Oncogene RHO H9,Ras homolog gene family member C,RAS related homolog 9,RHO C,Rho cDNA clone 9,Rho related GTP binding protein RhoC,Rho-related GTP-binding protein RhoC,rhoC,RhoC GTPase,RHOC,RHOH 9,RHOH9,Small GTP binding protein RhoC

Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molekulargewicht

Observed_MW: 22kDa

Calculated_MW: 22kDa

Gen-ID 389
UniProt P08134
Pathways WNT Signalweg, Cell-Cell Junction Organization
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Ras Homolog Gene Family, Member C (RHOC) antibody (ABIN6567006) Western blot analysis of extracts of various cell lines, using RHOC antibody.
Image no. 2 for anti-Ras Homolog Gene Family, Member C (RHOC) antibody (ABIN6567006) Immunofluorescence analysis of HeLa cells using RHOC antibody.