RHOC Antikörper

Produktnummer ABIN6567006

Dieses Anti-RHOC-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RHOC in WB und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für RHOC Antikörper (ABIN6567006)

Target: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHOC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-RHOC Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human RHOC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IF 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RHOC

Target: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Andere Bezeichnung: RHOC

Hintergrund:

Synonyms: Aplysia RAS-related homolog 9,ARH 9,ARH9,ARHC,H9,MGC1448,MGC61427,Oncogene RHO H9,Ras homolog gene family member C,RAS related homolog 9,RHO C,Rho cDNA clone 9,Rho related GTP binding protein RhoC,Rho-related GTP-binding protein RhoC,rhoC,RhoC GTPase,RHOC,RHOH 9,RHOH9,Small GTP binding protein RhoC

Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molekulargewicht:

Observed_MW: 22kDa

Calculated_MW: 22kDa

Gen-ID: 389

UniProt: P08134

Pathways: WNT Signalweg, Cell-Cell Junction Organization