COL11A2 Antikörper

Produktnummer ABIN6566947

Produktdetails anti-COL11A2 Antikörper

Target: COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL11A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human COL11A2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu COL11A2

Target: COL11A2 (Collagen, Type XI, alpha 2 (COL11A2))

Andere Bezeichnung: COL11A2 (COL11A2 Produkte)

Synonyme: col11a2 antikoerper, MGC89039 antikoerper, COL11A2 antikoerper, RING3 antikoerper, DFNA13 antikoerper, DFNB53 antikoerper, FBCG2 antikoerper, HKE5 antikoerper, PARP antikoerper, STL3 antikoerper, collagen, type XI, alpha 2 antikoerper, collagen type XI alpha 2 chain antikoerper, bromodomain containing 2 antikoerper, col11a2 antikoerper, COL11A2 antikoerper, BRD2 antikoerper, Col11a2 antikoerper

Hintergrund:

Synonyms: COBA2,COL11A2,Collagen alpha 2(XI),Collagen alpha-2(XI) chain,Collagen type XI alpha 2,Collagen XI a2,DAQB-79P13.8,DFNA13,DFNB53,FBCG2,HGNC:2187,HKE5,PARP,Pro a2 chain of collagen type XI,STL3

Background: This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.

Molekulargewicht:

Observed_MW: 150kDa

Calculated_MW: 31kDa/159-171kDa

Gen-ID: 1302

UniProt: P13942

Pathways: RTK Signalweg, Sensory Perception of Sound, Chromatin Binding