COL11A2 Antikörper (Collagen, Type XI, alpha 2)

Details for Product anti-COL11A2 Antibody No. ABIN6566947
Target
Reaktivität
Human, Maus, Ratte
49
27
17
4
4
3
2
2
1
1
1
1
1
Wirt
Kaninchen
41
8
1
Klonalität
Polyklonal
Konjugat
Dieser COL11A2 Antikörper ist unkonjugiert
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
22
19
13
9
6
2
1
1
Optionen
Immunogen Recombinant protein of human COL11A2
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung COL11A2 (COL11A2 Antibody Abstract)
Hintergrund

Synonyms: COBA2,COL11A2,Collagen alpha 2(XI),Collagen alpha-2(XI) chain,Collagen type XI alpha 2,Collagen XI a2,DAQB-79P13.8,DFNA13,DFNB53,FBCG2,HGNC:2187,HKE5,PARP,Pro a2 chain of collagen type XI,STL3

Background: This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6.

Molekulargewicht

Observed_MW: 150kDa

Calculated_MW: 31kDa/159-171kDa

Gen-ID 1302
UniProt P13942
Pathways RTK Signalweg, Sensory Perception of Sound, Chromatin Binding
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Collagen, Type XI, alpha 2 (COL11A2) antibody (ABIN6566947) Western blot analysis of extracts of various cell lines, using COL11A2 antibody.