LOXL1 Antikörper (Lysyl Oxidase-Like 1)

Details for Product anti-LOXL1 Antibody No. ABIN6566806
Target
Reaktivität
Human, Maus, Ratte
52
23
10
4
4
3
3
2
2
1
Wirt
Kaninchen
55
5
Klonalität
Polyklonal
Konjugat
Dieser LOXL1 Antikörper ist unkonjugiert
9
9
3
1
1
1
1
1
1
Applikation
Western Blotting (WB)
47
22
17
10
7
6
5
4
3
2
1
1
Optionen
Immunogen Recombinant protein of human LOXL1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung LOXL1 (LOXL1 Antibody Abstract)
Hintergrund

Synonyms: Lysyl oxidase like 1,LOL,LOXL,Lysyl oxidase homolog 1,Lysyl oxidase like protein 1

Background: This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.

Molekulargewicht

Observed_MW: 80kDa

Calculated_MW: 63kDa

Gen-ID 4016
UniProt Q08397
Applikations-hinweise WB 1:1000 - 1:3000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Lysyl Oxidase-Like 1 (LOXL1) antibody (ABIN6566806) Western blot analysis of extracts of various cell lines, using LOXL1 antibody.