CRLF2 Antikörper

Produktnummer ABIN6566796

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CRLF2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für CRLF2 Antikörper (ABIN6566796)

Target: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRLF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CRLF2 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CRLF2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CRLF2

Target: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Andere Bezeichnung: CRLF2

Hintergrund:

Synonyms: CRL 2,CRL2,CRLF 2,Crlf2,CRLF2,CRLF2Y,Cytokine receptor CRL2 precusor,Cytokine receptor like 2,Cytokine receptor like factor 2,Cytokine receptor like factor 2 precursor,Cytokine receptor-like 2,Cytokine receptor-like factor 2,IL XR,IL-XR,ILXR,Thymic stromal derived lymphopoietin receptor,Thymic stromal lymphopoietin protein receptor,Thymic stromal lymphopoietin receptor,TSLP receptor,TSLPR

Background: This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.

Molekulargewicht:

Observed_MW: 50kDa

Calculated_MW: 26kDa/29kDa/42kDa

Gen-ID: 64109

UniProt: Q9HC73