IKAP/p150 Antikörper

Produktnummer ABIN6566783

Dieser Anti-IKAP/p150 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von IKAP/p150 in WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für IKAP/p150 Antikörper (ABIN6566783)

Target: IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IKAP/p150 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IKAP/p150 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human IKBKAP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000 - 1:4000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IKAP/p150

Target: IKAP/p150 (ELP1) (Elongator Complex Protein 1 (ELP1))

Andere Bezeichnung: IKBKAP

Hintergrund:

Synonyms: DKFZp781H1425,DYS,Dysautonomia (Riley Day syndrome hereditary sensory autonomic neuropathy type III),Elongator complex protein 1,ELP 1,ELP1,ELP1,FD,FLJ12497,IKAP,IkappaB kinase complex associated protein,IkappaB kinase complex-associated protein,ikbkap,IKI 3,IKI3,IKK complex associated protein,IKK complex-associated protein,Inhibitor of kappa light polypeptide gene enhancer in B cells kinase complex associated protein,OTTHUMP00000063889,p150,TOT 1,TOT1

Background: The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht:

Observed_MW: 150kDa

Calculated_MW: 150kDa

Gen-ID: 8518

UniProt: O95163