Desmocollin 1 Antikörper (DSC1)

Details for Product anti-DSC1 Antibody No. ABIN6566762
Target
Reaktivität
Human, Maus, Ratte
37
8
2
Wirt
Kaninchen
38
3
1
Klonalität
Polyklonal
Konjugat
Dieser Desmocollin 1 Antikörper ist unkonjugiert
3
2
2
2
2
2
1
1
1
1
1
1
Applikation
Western Blotting (WB)
33
23
14
5
5
4
3
2
2
2
1
Optionen
Immunogen Recombinant protein of human DSC1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung DSC1 (DSC1 Antibody Abstract)
Hintergrund

Synonyms: Cadherin family member 1,CDHF1,Desmocollin1,Desmosomal glycoprotein 2/3,DG2/DG3,DSC 1,DSC1

Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein.

Molekulargewicht

Observed_MW: 105kDa

Calculated_MW: 93kDa/99kDa

Gen-ID 1823
UniProt Q08554
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Desmocollin 1 (DSC1) antibody (ABIN6566762) Western blot analysis of extracts of various cell lines, using DSC1 antibody.