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Desmocollin 1 Antikörper

Der Kaninchen Polyklonal Anti-Desmocollin 1-Antikörper wurde für WB validiert. Er ist geeignet, Desmocollin 1 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN6566762

Kurzübersicht für Desmocollin 1 Antikörper (ABIN6566762)

Target

Alle Desmocollin 1 (DSC1) Antikörper anzeigen
Desmocollin 1 (DSC1)

Reaktivität

Human, Maus, Ratte

Wirt

  • 39
  • 4
  • 1
Kaninchen

Klonalität

  • 38
  • 6
Polyklonal

Konjugat

  • 30
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Desmocollin 1 Antikörper ist unkonjugiert

Applikation

  • 34
  • 20
  • 16
  • 10
  • 8
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Aufreinigung

    Affinity purification

    Immunogen

    Recombinant protein of human DSC1

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:500 - 1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Desmocollin 1 (DSC1)

    Andere Bezeichnung

    DSC1

    Hintergrund

    Synonyms: Cadherin family member 1,CDHF1,Desmocollin1,Desmosomal glycoprotein 2/3,DG2/DG3,DSC 1,DSC1

    Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein.

    Molekulargewicht

    Observed_MW: 105kDa

    Calculated_MW: 93kDa/99kDa

    Gen-ID

    1823

    UniProt

    Q08554
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