TLR7 Antikörper (Toll-Like Receptor 7)

Details for Product anti-TLR7 Antibody No. ABIN6566727
Target
Reaktivität
Human, Maus
135
73
27
3
3
3
2
1
1
1
1
Wirt
Kaninchen
134
19
2
1
Klonalität
Polyklonal
Konjugat
Dieser TLR7 Antikörper ist unkonjugiert
14
14
9
6
5
5
4
4
4
4
4
4
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC)
100
66
41
24
22
13
8
7
4
3
2
2
2
Optionen
Immunogen Recombinant protein of human TLR7
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung TLR7 (TLR7 Antibody Abstract)
Hintergrund

Synonyms: PRO285,TLR 7,Tlr7,TLR7,Toll like receptor 7,Toll-like receptor 7,UNQ248

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.

Molekulargewicht

Calculated_MW: 120kDa

Gen-ID 51284
UniProt Q9NYK1
Pathways TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
Applikations-hinweise IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Toll-Like Receptor 7 (TLR7) antibody (ABIN6566727) Immunohistochemistry of paraffin-embedded human thyroid cancer using TLR7 Antibody.
Image no. 2 for anti-Toll-Like Receptor 7 (TLR7) antibody (ABIN6566727) Immunofluorescence analysis of MCF-7 cells using TLR7 antibody.