LEF1 Antikörper

Produktnummer ABIN6566691

Dieses Anti-LEF1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LEF1 in WB. Geeignet für Human und Maus.

Kurzübersicht für LEF1 Antikörper (ABIN6566691)

Target: LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LEF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LEF1 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant Protein of human LEF1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LEF1

Target: LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

Andere Bezeichnung: LEF1

Hintergrund:

Synonyms: DKFZp586H0919,FLJ46390,LEF 1,LEF-1,Lef1,LEF1,Lymphoid enhancer binding factor 1,Lymphoid enhancer-binding factor 1,T cell specific transcription factor 1 alpha,T cell-specific transcription factor 1-alpha,TCF 1 alpha,TCF1 alpha,TCF1-alpha,TCF10,TCF1alpha,TCF7L3,Transcription factor T cell specific 1 alpha

Background: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 40kDa

Calculated_MW: 23kDa/31kDa/34kDa/35kDa/41kDa/42kDa/44kDa

Gen-ID: 51176

UniProt: Q9UJU2

Pathways: WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding