TJP2 Antikörper

Produktnummer ABIN6566621

Dieses Anti-TJP2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TJP2 in WB und IHC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für TJP2 Antikörper (ABIN6566621)

Target: TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TJP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TJP2 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human TJP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TJP2

Target: TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))

Andere Bezeichnung: TJP2

Hintergrund:

Synonyms: C9DUPq21.11,DFNA51,DUP9q21.11,Friedreich ataxia region gene X104 (tight junction protein ZO-2),MGC26306 ,PFIC4,Tight junction protein 2,Tight junction protein ZO 2,Tight junction protein ZO-2,TJP2,X104,ZO 2,ZO-2,ZO2,ZO2,Zona occludens 2,Zona occludens protein 2,Zonula occludens protein 2

Background: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Molekulargewicht:

Observed_MW: 160kDa

Calculated_MW: 111-137kDa

Gen-ID: 9414

UniProt: Q9UDY2