TJP2 Antikörper (AA 951-1190)
Kurzübersicht für TJP2 Antikörper (AA 951-1190) (ABIN1683322)
Target
Alle TJP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 951-1190
-
Sequenz
- RSSEPVQHEE SIRKPSPEPR AQMRRAASSD QLRDNSPPPA FKPEPPKAKT QNKEESYDFS KSYEYKSNPS AVAGNETPGA STKGYPPPVA AKPTFGRSIL KPSTPIPPQE GEEVGESSEE QDNAPKSVLG KVKIFEKMDH KARLQRMQEL QEAQNARIEI AQKHPDIYAV PIKTHKPDPG TPQHTSSRPP EPQKAPSRPY QDTRGSYGSD AEEEEYRQQL SEHSKRGYYG QSARYRDTEL
-
Kreuzreaktivität
- Human, Maus, Ratte
-
Produktmerkmale
- Polyclonal Antibodies
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 951-1190 of human TJP2 (NP_004808.2).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB,1:500 - 1:2000,IP,1:50 - 1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))
-
Andere Bezeichnung
- TJP2
-
Hintergrund
- This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.,TJP2,C9DUPq21.11,DFNA51,DUP9q21.11,PFIC4,X104,ZO2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,TJP2
-
Molekulargewicht
- 111-137 kDa
-
Gen-ID
- 9414
-
UniProt
- Q9UDY2
Target
-