NUMA1 Antikörper (Nuclear Mitotic Apparatus Protein 1)

Details for Product anti-NUMA1 Antibody No. ABIN6566605
Target
Reaktivität
Human, Maus, Ratte
110
39
22
3
3
2
2
1
1
1
1
1
1
Wirt
Kaninchen
79
31
Klonalität
Polyklonal
Konjugat
Dieser NUMA1 Antikörper ist unkonjugiert
7
5
4
4
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
48
31
26
23
23
19
18
15
9
7
3
2
1
1
1
Optionen
Immunogen Recombinant protein of human NUMA1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung NUMA1
Hintergrund

Synonyms: Centrophilin stabilizes mitotic spindle in mitotic cells,NMP 22,Nuclear matrix protein 22,Nuclear mitotic apparatus protein 1,Nuclear mitotic apparatus protein,NUMA 1,NUMA,NuMA protein,NUMA1,NUMA1,SP H antigen,SP-H antigen,Structural nuclear protein

Background: This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 238kDa

Calculated_MW: 109kDa/200kDa/201kDa/236kDa/238kDa

Gen-ID 4926
UniProt Q14980
Pathways Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization, M Phase
Applikations-hinweise WB 1:200 - 1:1000 IHC 1:50 - 1:100
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) antibody (ABIN6566605) Western blot analysis of extracts of various cell lines, using NUMA1 antibody.
Image no. 2 for anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) antibody (ABIN6566605) Immunohistochemistry of paraffin-embedded human stomach using NUMA1 antibody.
Image no. 3 for anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) antibody (ABIN6566605) Immunohistochemistry of paraffin-embedded rat heart using NUMA1 antibody.
Image no. 4 for anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) antibody (ABIN6566605) Immunohistochemistry of paraffin-embedded mouse stomach using NUMA1 antibody.