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Lamin A/C Antikörper

LMNA Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6566533
  • Target Alle Lamin A/C (LMNA) Antikörper anzeigen
    Lamin A/C (LMNA)
    Reaktivität
    • 136
    • 79
    • 75
    • 26
    • 15
    • 13
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 100
    • 45
    • 2
    • 1
    Kaninchen
    Klonalität
    • 102
    • 46
    Polyklonal
    Konjugat
    • 111
    • 9
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Lamin A/C Antikörper ist unkonjugiert
    Applikation
    • 117
    • 54
    • 52
    • 47
    • 31
    • 29
    • 28
    • 17
    • 12
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human Lamin C (NP_005563.1).
    Isotyp
    IgG
    Top Product
    Discover our top product LMNA Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Lamin A/C (LMNA)
    Andere Bezeichnung
    Lamin A/C (LMNA Produkte)
    Hintergrund
    The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
    Molekulargewicht

    Observed_MW: 74kDa

    Calculated_MW: 62-74kDa

    Gen-ID
    4000
    UniProt
    P02545
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, ER-Nucleus Signaling, Protein targeting to Nucleus
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