ZP4 Antikörper (C-Term)

Produktnummer ABIN656652

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-ZP4 Antikörper (Klon RB32332) (ABIN656652) detektiert spezifisch ZP4 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ZP4 Antikörper (C-Term) (ABIN656652)

Target: ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB32332

Produktdetails anti-ZP4 Antikörper

Bindungsspezifität: AA 445-474, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human ZP4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: ZP4 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-ZP4 Antikörper (ABIN656652)

Mask, Schoenecker, Kane, Ransom, Bruemmer: "Serum antibody immunoreactivity to equine zona protein after SpayVac vaccination." in: Theriogenology, Vol. 84, Issue 2, pp. 261-7, (2015) (PubMed).

Details zu ZP4

Target: ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

Andere Bezeichnung: ZP4

Hintergrund: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4.

Molekulargewicht: 59400

Gen-ID: 57829

NCBI Accession: NP_067009

UniProt: Q12836