BAK1 Antikörper (BCL2-Antagonist/killer 1)

Details for Product anti-BAK1 Antibody No. ABIN6566497
Target
Reaktivität
Human, Maus, Ratte
107
44
30
4
2
1
1
1
1
Wirt
Kaninchen
90
9
8
1
Klonalität
Polyklonal
Konjugat
Dieser BAK1 Antikörper ist unkonjugiert
6
4
4
3
3
3
3
3
3
3
3
3
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
81
44
43
20
20
13
12
11
7
5
3
1
1
1
Optionen
Immunogen A synthetic peptide of human BAK1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung BAK1 (BAK1 Antibody Abstract)
Hintergrund

Synonyms: Apoptosis regulator BAK,BAK,BAK like,Bak NT,BAK,Bak1,Bcl 2 homologous antagonist/killer,Bcl 2 like 7 protein,Bcl-2 homologous antagonist/killer,Bcl-2-like protein 7,BCL2 antagonist/killer 1,Bcl2 like 7 Protein,Bcl2-L-7,BCL2L7,CDN1,Cell death inhibitor 1,MGC117255,MGC3887,NBak,Pro apoptotic protein BAK

Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Molekulargewicht

Observed_MW: 26kDa

Calculated_MW: 16kDa/23kDa

Gen-ID 578
UniProt Q16611
Pathways Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded protein response
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-BCL2-Antagonist/killer 1 (BAK1) antibody (ABIN6566497) Western blot analysis of extracts of various cell lines, using BAK1 Antibody.
Image no. 2 for anti-BCL2-Antagonist/killer 1 (BAK1) antibody (ABIN6566497) Immunofluorescence analysis of HeLa cells using BAK1 antibody.