SF3B3 Antikörper (C-Term)
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- Target Alle SF3B3 Antikörper anzeigen
- SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
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Bindungsspezifität
- AA 1046-1074, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SF3B3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Homologie
- B, M
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This SF3B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1046-1074 amino acids from the C-terminal region of human SF3B3.
- Klon
- RB32074
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product SF3B3 Primärantikörper
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- Applikationshinweise
- WB: 1:1000. WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- SF3B3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
- Andere Bezeichnung
- SF3B3 (SF3B3 Produkte)
- Hintergrund
- This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
- Molekulargewicht
- 135577
- Gen-ID
- 23450
- NCBI Accession
- NP_036558
- UniProt
- Q15393
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