IRF4 Antikörper (AA 164-191)

Produktnummer ABIN656568

Dieses Anti-IRF4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IRF4 in WB und FACS. Geeignet für Human.

Kurzübersicht für IRF4 Antikörper (AA 164-191) (ABIN656568)

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: RB17417

Produktdetails anti-IRF4 Antikörper

Bindungsspezifität: AA 164-191

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This IRF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-191 amino acids from the Central region of human IRF4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: IRF4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu IRF4

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Andere Bezeichnung: IRF4

Hintergrund: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

Molekulargewicht: 51772

Gen-ID: 3662

NCBI Accession: NP_001182215, NP_002451

UniProt: Q15306

Pathways: Chromatin Binding