FAP Antikörper

Produktnummer ABIN656472

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-FAP Antikörper (Klon RB07288) (ABIN656472) detektiert spezifisch FAP in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für FAP Antikörper (ABIN656472)

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB07288

Produktdetails anti-FAP Antikörper

Aufreinigung: This antibody is purified through a protein A column, followed by dialysis against PBS.

Immunogen: This FAP antibody is generated from rabbits immunized with the protein of human FAP.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: His6-FAP Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-FAP Antikörper (ABIN656472)

Yang, Lin, Shi, Li, Liu, Yin, Dang, Chu, Fan, He: "FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling." in: Cancer research, Vol. 76, Issue 14, pp. 4124-35, (2016) (PubMed).

Details zu FAP

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Andere Bezeichnung: FAP

Hintergrund: The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

Molekulargewicht: 87713

Gen-ID: 2191

NCBI Accession: NP_004451

UniProt: Q12884

Pathways: Tube Formation