SEPN1 Antikörper (C-Term)

Produktnummer ABIN656385

Dieses Anti-SEPN1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SEPN1 in WB und IHC (p). Geeignet für Human.

Kurzübersicht für SEPN1 Antikörper (C-Term) (ABIN656385)

Target: SEPN1 (Selenoprotein N, 1 (SEPN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEPN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB31326

Produktdetails anti-SEPN1 Antikörper

Bindungsspezifität: AA 417-445, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SEPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 417-445 amino acids from the C-terminal region of human SEPN1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: SEPN1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu SEPN1

Target: SEPN1 (Selenoprotein N, 1 (SEPN1))

Andere Bezeichnung: SEPN1

Hintergrund: This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Mutations in this gene cause the classical phenotype of multiminicore disease and congenital muscular dystrophy with spinal rigidity and restrictive respiratory syndrome. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molekulargewicht: 65813

Gen-ID: 57190

NCBI Accession: NP_065184, NP_996809

UniProt: Q9NZV5

Pathways: Skeletal Muscle Fiber Development