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DDR1 Antikörper

DDR1 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal 51D6 unconjugated
Produktnummer ABIN6559822
  • Target Alle DDR1 Antikörper anzeigen
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    Reaktivität
    • 85
    • 34
    • 34
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 87
    • 12
    • 1
    Maus
    Klonalität
    • 86
    • 13
    • 1
    Monoklonal
    Konjugat
    • 50
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser DDR1 Antikörper ist unkonjugiert
    Applikation
    • 76
    • 39
    • 26
    • 26
    • 20
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Verwendungszweck
    Anti-Hu CD167a Purified
    Spezifität
    The mouse monoclonal antibody 51D6 recognizes an extracellular epitope of CD167a, an approximately 97-101 kDa receptor tyrosine kinase expressed mainly on epithelial cells, but also on B cells and dendritic cells.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    CD167a-transfected NIH-3T3 cells
    Klon
    51D6
    Isotyp
    IgM
    Top Product
    Discover our top product DDR1 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    Andere Bezeichnung
    CD167a (DDR1 Produkte)
    Hintergrund
    Discoidin domain receptor tyrosine kinase 1,CD167a, also known as e.g. discoidin domain receptor tyrosine kinase 1 (DDR1), tyrosine kinase receptor E (TRKE), cell adhesion kinase (CAK), or neuroepithelial tyrosine kinase 4 (NEP, NTRK4), is a transmembrane receptor tyrosine kinase expressed predominantly in epithelial cells. It has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. After binding to fibrilar collagens I, II, III, V, or basement membrane collagens IV and VIII, CD167a becomes activated and autophosphorylated and transduces collagen-induced signaling.,EDDR1, MCK10, NTRK4, PTK3A, RTK6, CAK, TRKE, DDR1
    Gen-ID
    780
    UniProt
    Q08345
    Pathways
    RTK Signalweg, Smooth Muscle Cell Migration
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