HOPX Antikörper (C-Term)

Produktnummer ABIN655402

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HOPX in WB und FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für HOPX Antikörper (C-Term) (ABIN655402)

Target: HOPX (HOP Homeobox (HOPX))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOPX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: RB18900

Produktdetails anti-HOPX Antikörper

Bindungsspezifität: AA 39-67, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HOPX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-67 amino acids from the C-terminal region of human HOPX.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-HOPX Antikörper (ABIN655402)

Kovárová, Plachy, Kosla, Trejbalová, ?ermák, Hejnar: "Downregulation of HOPX controls metastatic behavior in sarcoma cells and identifies genes associated with metastasis." in: Molecular cancer research : MCR, Vol. 11, Issue 10, pp. 1235-47, (2013) (PubMed).

Details zu HOPX

Target: HOPX (HOP Homeobox (HOPX))

Andere Bezeichnung: HOPX

Hintergrund: The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq].

Gen-ID: 84525

NCBI Accession: NP_001138931, NP_001138932, NP_115884, NP_631957, NP_631958

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation