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Endothelin 3 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-Endothelin 3-Antikörper wurde für WB validiert. Er ist geeignet, Endothelin 3 in Proben von Human zu detektieren.
Produktnummer ABIN655169

Kurzübersicht für Endothelin 3 Antikörper (C-Term) (ABIN655169)

Target

Alle Endothelin 3 (EDN3) Antikörper anzeigen
Endothelin 3 (EDN3)

Reaktivität

  • 32
  • 6
  • 4
  • 2
  • 2
  • 1
Human

Wirt

  • 33
  • 3
Kaninchen

Klonalität

  • 34
  • 2
Polyklonal

Konjugat

  • 24
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Endothelin 3 Antikörper ist unkonjugiert

Applikation

  • 24
  • 13
  • 8
  • 5
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)

Klon

RB18967
  • Bindungsspezifität

    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 168-197, C-Term

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This EDN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human EDN3.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    Endothelin 3 (EDN3)

    Andere Bezeichnung

    EDN3

    Hintergrund

    The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

    Molekulargewicht

    25454

    Gen-ID

    1908

    NCBI Accession

    NP_000105, NP_996915, NP_996916, NP_996917

    UniProt

    P14138

    Pathways

    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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