INHBB Antikörper (C-Term)

Produktnummer ABIN655083

Dieses Anti-INHBB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von INHBB in WB und IHC (p). Geeignet für Human und Maus.

Kurzübersicht für INHBB Antikörper (C-Term) (ABIN655083)

Target: INHBB (Inhibin, beta B (INHBB))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INHBB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB23814

Produktdetails anti-INHBB Antikörper

Bindungsspezifität: AA 369-397, C-Term

Homologie: B, C, Pig, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This INHBB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-397 amino acids from the C-terminal region of human INHBB.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:4000. WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu INHBB

Target: INHBB (Inhibin, beta B (INHBB))

Andere Bezeichnung: INHBB

Hintergrund: The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

Molekulargewicht: 45122

Gen-ID: 3625

NCBI Accession: NP_002184

UniProt: P09529

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion