Serotonin Receptor 2B Antikörper (C-Term)

Produktnummer ABIN655076

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-Serotonin Receptor 2B Antikörper wird verwendet zum Nachweis von Serotonin Receptor 2B in Proben von Human, Ratte und Maus. Er wurde validiert für WB und IHC (p).

Kurzübersicht für Serotonin Receptor 2B Antikörper (C-Term) (ABIN655076)

Target: Serotonin Receptor 2B (HTR2B) (5-Hydroxytryptamine (serotonin) Receptor 2B (HTR2B))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB20470

Produktdetails anti-Serotonin Receptor 2B Antikörper

Bindungsspezifität: AA 408-435, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HTR2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-435 amino acids from the C-terminal region of human HTR2B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:2000. IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Serotonin Receptor 2B Antikörper (ABIN655076)

Li, Sun, Li, Zhai, Wang, Chen, Lu: "Chronic restraint stress reduces carbon tetrachloride-induced liver fibrosis." in: Experimental and therapeutic medicine, Vol. 11, Issue 6, pp. 2147-2152, (2016) (PubMed).

Details zu Serotonin Receptor 2B

Target: Serotonin Receptor 2B (HTR2B) (5-Hydroxytryptamine (serotonin) Receptor 2B (HTR2B))

Andere Bezeichnung: HTR2B

Hintergrund: Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.

Molekulargewicht: 54298

Gen-ID: 3357

NCBI Accession: NP_000858

UniProt: P41595

Pathways: JAK-STAT Signalweg, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process