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E2F2 Antikörper (AA 258-286)

Dieses Anti-E2F2-Antikörper ist ein Rabbit Polyclonal-Antikörper zur Detektion von E2F2 in WB. Geeignet für Human, Mouse.
Produktnummer ABIN654438

Kurzübersicht für E2F2 Antikörper (AA 258-286) (ABIN654438)

Target

Alle E2F2 Antikörper anzeigen
E2F2 (E2F Transcription Factor 2 (E2F2))

Reaktivität

  • 61
  • 40
  • 18
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Human, Maus

Wirt

  • 54
  • 7
Kaninchen

Klonalität

  • 49
  • 12
Polyklonal

Konjugat

  • 37
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser E2F2 Antikörper ist unkonjugiert

Applikation

  • 43
  • 20
  • 13
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Klon

RB27633
  • Bindungsspezifität

    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 258-286

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This E2F2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-286 amino acids from the Central region of human E2F2.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:2000. WB: 1:1000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Target

    E2F2 (E2F Transcription Factor 2 (E2F2))

    Andere Bezeichnung

    E2F2

    Hintergrund

    E2F2 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46 % amino acid identity to E2F1. [provided by RefSeq].

    Molekulargewicht

    47506

    Gen-ID

    1870

    NCBI Accession

    NP_004082

    UniProt

    Q14209

    Pathways

    Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication
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