MED25 Antikörper (AA 112-140)

Produktnummer ABIN654162

Dieses Anti-MED25-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MED25 in WB und IHC (p). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für MED25 Antikörper (AA 112-140) (ABIN654162)

Target: MED25 (Mediator Complex Subunit 25 (MED25))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MED25 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB24225

Produktdetails anti-MED25 Antikörper

Bindungsspezifität: AA 112-140

Homologie: B

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MED25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids of human MED25.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-MED25 Antikörper (ABIN654162)

Han, Rha, Chi: "MED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells." in: PLoS ONE, Vol. 7, Issue 8, pp. e44007, (2013) (PubMed).

Details zu MED25

Target: MED25 (Mediator Complex Subunit 25 (MED25))

Andere Bezeichnung: MED25

Hintergrund: This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq].

Molekulargewicht: 78171

Gen-ID: 81857

NCBI Accession: NP_112235

UniProt: Q71SY5

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response