WASP Antikörper (AA 116-144)

Produktnummer ABIN653830

Produktdetails anti-WASP Antikörper

Target: WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

Bindungsspezifität: AA 116-144

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WASP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This WAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-144 amino acids from the Central region of human WAS.

Klon: RB23643

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu WASP

Target: WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

Andere Bezeichnung: WAS (WAS Produkte)

Synonyme: IMD2 antikoerper, SCNX antikoerper, THC antikoerper, THC1 antikoerper, WASP antikoerper, U42471 antikoerper, WASp antikoerper, Wasp antikoerper, imd2 antikoerper, thc antikoerper, thc1 antikoerper, was antikoerper, wasp antikoerper, wu:fk81c08 antikoerper, zgc:64164 antikoerper, Wiskott-Aldrich syndrome antikoerper, neural Wiskott-Aldrich syndrome protein antikoerper, wiskott-aldrich syndrome protein antikoerper, Wiskott-Aldrich syndrome L homeolog antikoerper, Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b antikoerper, WAS antikoerper, LOC5578888 antikoerper, CpipJ_CPIJ006699 antikoerper, Was antikoerper, was.L antikoerper, wasb antikoerper

Hintergrund: The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients.

Molekulargewicht: 52913

Gen-ID: 7454

NCBI Accession: NP_000368

UniProt: P42768