CD47 Antikörper (C-Term)

Produktnummer ABIN653081

Produktdetails anti-CD47 Antikörper

Target: CD47

Bindungsspezifität: AA 288-315, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD47 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CD47 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-315 amino acids from the C-terminal region of human CD47.

Klon: RB23121

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CD47

Target: CD47

Andere Bezeichnung: CD47 (CD47 Produkte)

Synonyme: IAP antikoerper, MER6 antikoerper, OA3 antikoerper, 9130415E20Rik antikoerper, AA407862 antikoerper, AI848868 antikoerper, AW108519 antikoerper, B430305P08Rik antikoerper, Itgp antikoerper, CD47/IAP antikoerper, alkaline phosphatase, intestinal antikoerper, CD47 molecule antikoerper, CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antikoerper, Cd47 molecule antikoerper, ALPI antikoerper, CD47 antikoerper, Cd47 antikoerper

Hintergrund: CD47 antigen, also known as integrin associated protein (IAP), has a very broad tissue distribution. CD47 is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. There are approximately 50.000 CD47 Molecules per erythrocyte. The glycoprotein is deficient in erythrocytes of the rare Rh null phenotype. CD47 is a heavily N glycosylated cell membrane glycoprotein of apparent molecular weight 47-52 kDa. It may play a role as a signaltransducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells.

Gen-ID: 961

NCBI Accession: NP_001768, NP_942088

UniProt: Q08722