14-3-3 zeta Antikörper (AA 65-93)

Produktnummer ABIN652428

Dieses Anti-14-3-3 zeta-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von 14-3-3 zeta in WB, IHC (p) und FACS. Geeignet für Human und Maus. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für 14-3-3 zeta Antikörper (AA 65-93) (ABIN652428)

Target: 14-3-3 zeta (YWHAZ)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser 14-3-3 zeta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: RB22149

Produktdetails anti-14-3-3 zeta Antikörper

Bindungsspezifität: AA 65-93

Homologie: B, C, Rat, Sh

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This YWHAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-93 amino acids from the Central region of human YWHAZ.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-14-3-3 zeta Antikörper (ABIN652428)

Joshi, Su, Chandramouli, Khoo, Jeong, Young, Lessey, Fazleabas: "Altered expression of microRNA-451 in eutopic endometrium of baboons (Papio anubis) with endometriosis." in: Human reproduction (Oxford, England), Vol. 30, Issue 12, pp. 2881-91, (2015) (PubMed).

Details zu 14-3-3 zeta

Target: 14-3-3 zeta (YWHAZ)

Andere Bezeichnung: YWHAZ

Hintergrund: YWHAZ belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for the gene. Both variants encode the same protein, however, they are differentially expressed in hematopoietic cells.

Molekulargewicht: 27745

Gen-ID: 7534

NCBI Accession: NP_001129171, NP_001129172, NP_001129173, NP_001129174, NP_003397, NP_663723

UniProt: P63104

Pathways: Apoptose, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location