Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VLDLR in WB, FACS und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This VLDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 484-510 amino acids from the Central region of human VLDLR.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Viall, Chen, Stone, Chamley: "Human extravillous trophoblasts bind but do not internalize antiphospholipid antibodies." in: Placenta, Vol. 42, pp. 9-16, (2016) (PubMed).
Target
VLDLR
(Very Low Density Lipoprotein Receptor (VLDLR))
Andere Bezeichnung
VLDLR
Hintergrund
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq].