TUBB3 Antikörper (AA 36-63)

Produktnummer ABIN651938

Der Kaninchen Polyklonal Anti-TUBB3-Antikörper wurde für WB, FACS und IHC (p) validiert. Er ist geeignet, TUBB3 in Proben von Human und Maus zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für TUBB3 Antikörper (AA 36-63) (ABIN651938)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUBB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB21098

Produktdetails anti-TUBB3 Antikörper

Bindungsspezifität: AA 36-63

Homologie: B, Pr, Rat, C

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TUBB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids of human TUBB3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-TUBB3 Antikörper (ABIN651938)

Kazmierczak, Kazmierczak, Peng, Harris, Shah, Puel, Lenoir, Franco, Schwander: "Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 37, Issue 13, pp. 3447-3464, (2017) (PubMed).

Jeong, Martchenko, Cohen: "Calpain-dependent cytoskeletal rearrangement exploited for anthrax toxin endocytosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 42, pp. E4007-15, (2013) (PubMed).

Details zu TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Andere Bezeichnung: TUBB3

Hintergrund: Beta III tubulin is abundant in the central and peripheral nervous systems (CNS and PNS) where it is prominently expressed during fetal and postnatal development. As exemplified in cerebellar and sympathoadrenal neurogenesis, the distribution of beta III is neuron-associated, exhibiting distinct temporospatial gradients according to the regional neuroepithelia of origin. However, transient expression of this protein is also present in the subventricular zones of the CNS comprising putative neuronal- and/or glial precursor cells, as well as in Kulchitsky neuroendocrine cells of the fetal respiratory epithelium. This temporally restricted, potentially non-neuronal expression may have implications in the identification of presumptive neurons derived from embryonic stem cells.

Molekulargewicht: 50433

Gen-ID: 10381

NCBI Accession: NP_001184110, NP_006077

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase