BBS10 Antikörper (C-Term)

Produktnummer ABIN651074

Der Kaninchen Polyklonal Anti-BBS10-Antikörper wurde für WB und FACS validiert. Er ist geeignet, BBS10 in Proben von Human zu detektieren.

Kurzübersicht für BBS10 Antikörper (C-Term) (ABIN651074)

Target: BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BBS10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Klon: RB24715

Produktdetails anti-BBS10 Antikörper

Bindungsspezifität: AA 515-544, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BBS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 515-544 amino acids from the C-terminal region of human BBS10.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu BBS10

Target: BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

Andere Bezeichnung: BBS10

Hintergrund: BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes.

Molekulargewicht: 80838

Gen-ID: 79738

NCBI Accession: NP_078961

UniProt: Q8TAM1