BBS10 Antikörper (C-Term)

Produktnummer ABIN2788220

Der Kaninchen Polyklonal anti-BBS10 Antikörper (ABIN2788220) detektiert spezifisch BBS10 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Kaninchen.

Kurzübersicht für BBS10 Antikörper (C-Term) (ABIN2788220)

Target: BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

Reaktivität: Human, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BBS10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BBS10 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: BBS10 Antibody - C-terminal region

Sequenz: SQTGLESVMG KYQLLTSVLQ CLTKILTIDM VITVKRHPQK VHNQDSEDEL

Homologie: Human: 100%, Rabbit: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against BBS10. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BBS10

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59803-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu BBS10

Target: BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

Andere Bezeichnung: BBS10

Hintergrund:

Background Information: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10.

Gene Name: Bardet-Biedl syndrome 10

Alternative Symbols: C12orf58

Protein Name: Bardet-Biedl syndrome 10 protein

Molekulargewicht: 81kDa

Gen-ID: 79738

NCBI Accession: NP_078961

UniProt: Q8TAM1